Why Is Blood Volume Measurement Important?

The Smallest Volume is the Most Vital for Survival

It is crucial to differentiate between interstitial overload and intravascular overload. The BVA-100 blood test directly quantifies the intravascular blood, plasma and red cell giving you actionable information you need to achieve optimal fluid management.

Interstital: 11-13 L | Intracellular: 27-30 L | Intravascular: 3.0-3.5 L

Heterogeneity in Total Blood Volume & Red Blood Cell Volume
Status is Common - Once Size Treatment Does Not Fit All

Frequency Distribution of Quantitated Volume

Deficit/Excess at Admission (n = 50)

The extent, composition, and distribution of volume overload in decompensated heart failure are highly variable, and this variability needs to be taken into account in the approach to individualized therapy.

Wayne L. Miller, M.D., Mayo Clinic

Managing Volume Derangement is a Challenge with High Stakes

The Goal: Get the Patient to Their Optimal Blood Volume

Indirect Measures Offer Low Clinical Utility as Indicators of
True Intravascular Volume Status

Clinical signs and symptoms typically describe fluid predominantly in the interstitial compartment. Hemodynamics, biomarkers and other common indirect measures can be costly, invasive, and are neither sensitive nor specific indicators of actual intravascular volume status.

Pressure is Not Volume – Volume is Not Pressure

Neither CVP, PCWP, nor dPAP accurately reflect intravascular volume status. Quantitative blood volume measurement (BVA) and cardiac hemodynamics provide complementary but different information.

Is the increase in pressure due to vasconstriction or volume expansion?

Patient with the Same Hct May Be Highly Discordant
in True Red Blood Cell Volume Status

The BVA is a method that provides an accurate measure of actual blood volume and gives researchers and clinicians the opportunity to measure the blood volume as opposed to estimate it. Our research essentially shows that reliance on surrogate markers of volume could be problematic. This provides an avenue to better understand our approach to patients with heart failure.

Marat Fudim, M.D., Duke University

BVA-100 Test Solution

Hospitals and clinicians struggle with readmissions, mortality and wasted resources. The BVA-100 test provides clinicians with accurate, actionable data to optimize treatment plans and individualize care improving outcomes and reducing duration and cost of care.

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Partner With the Dedicated Leader in BVA

As the pioneer in blood volume analysis, Daxor provides education and the resources needed to ensure easy onboarding along with continuing support to drive maximum value from your BVA system throughout your facility. With a long-standing commitment to improving care and numerous studies validating our technology, Daxor is completely focused on advancing healthcare by enabling optimal fluid management with blood volume analysis. Our vision is optimal blood volume for all.

Volume is Vital. End the Debate With Daxor.

Call us at 865-425-0555.


Daxor Corporation is the global leader in blood volume measurement technology focused on blood volume testing innovation. We developed and market the BVA-100 (Blood Volume Analyzer), the first diagnostic blood test cleared by the FDA to provide safe, accurate, objective quantification of blood volume status and composition compared to patient-specific norms for use in a broad range of medical and surgical conditions.

Daxor Corporation – 107 Meco Lane, Oak Ridge, TN 37830
Phone: 865-425-0555 | Fax: 865-425-0551
info@daxor.com | daxor.com

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