Optimal Volume Management is Key to Survivability
Oxygenation by the lungs and pumping of the heart carries
optimal blood volume to supply oxygen to vital organs.
Blood Volume Measurement Provides Actionable Information to Achieve Optimal Fluid Management
New data in journal Critical Care, N = 6
BVA identified true volume status vs. clinical exam in 6/6 patients
50% identified as hypovolemic/anemic
67% elevated albumin transudation rate
“Fluid resuscitation in COVID-19 patients could benefit from knowing the blood volume and capillary leak rate of patients as they are subject to significant leak and related hypovolemia.”
Yan Bakker, M.D.
Blood Volume Measurements Improved Survival
Prospective randomized control trial in Surgical ICU
N=100, 70% Septic Shock / Sepsis / ARDS
66% reduction in mortality
20% reduction in LOS
36 hour earlier treatment decisions
44% change in treatment strategy
“An important aspect of care was the earlier treatment of intravascular volume deviations in the BVA group, before the abnormality became clinically manifested.”
Mihae Yu, M.D. – Queens Hospital
66% reduction in mortality
44% change in treatment strategy
Capillary leak rate shown to be predictive of ICU mortality in cohort with 70% respiratory failure.
Rate at which the albumin transudates out of circulation shown to be predictive of ICU mortality in cohort with 70% respiratory failure.
Retrospective Study in Surgical ICU
N = 164
BVA Increases Ventilator Availability by Shortening Days on Ventilator
Adapted from CDC / Economist
Knowledge of volume status avoids dangers of under and over resuscitation, ensuring fluid treatment interventions in accordance with measured volume derangements.
“One of the mysteries of post-acute sequelae SARS-CoV-2 is the basis for non-specific, enduring, debilitating symptoms such as ‘brain fog’ executive dysfunction, exercise intolerance, and orthostatic intolerance. There are several potential mechanisms, including low blood volume.”
Dr. David S. Goldstein, M.D., Ph.D., National Institute of Neurological Disorders and Stroke
FAQs
How does BVA help manage patients with Respiratory Distress, Sepsis/Septic Shock & ARDS?
BVA precisely measures total blood volume and red blood cell volume with 98% accuracy, guiding an effective, patient-specific fluid management strategy for optimal results.
What is the benefit of knowing the Albumin Transudation Slope?
Albumin Transudation Slope provides the rate at which the albumin transudates out of circulation through the capillary bed. A rate of approximately 0.25% per minute is considered normal. In a patient with increased capillary permeability, this rate may increase.
Is the BVA test FDA-cleared and available now?
The BVA test is FDA-cleared with over 45,000 tests used to date to assess blood volume in a network of hospitals across the U.S.
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