Clinical Evidence

Significantly Improved Outcomes in Hospitalized Heart Failure:

Heart Failure Outcomes with Volume-Guided Management.

John E. Strobeck, Jonathan Feldschuh and Wayne Miller
JACC: Heart Failure
Volume 6, Issue 11, November 2018
DOI: 10.1016/j.jchf.2018.06.017

Extremely Cost-Effective Improvement in Patient Life Span in Hospitalized Heart Failure:

Cost-Effectiveness Analysis of Early Blood Volume-Guided Management in Hospitalized Heart Failure.

John E. Strobeck, Jonathan Feldschuh, Brent A. Williams and Wayne L. Miller
Presented at HFSA 2020 Virtual Conference

Lower ICU Mortality:

A prospective randomized trial using blood volume analysis in addition to pulmonary artery catheter, compared with pulmonary artery catheter alone, to guide shock resuscitation in critically ill surgical patients.

Yu M, Pei K, Moran S, Edwards KD, Domingo S, Steinemann S, Ghows M, Takiguchi S, Tan A, Lurie F, Takanishi D Jr.
Shock. 2011 Mar;35(3):220-8. doi: 10.1097/SHK.0b013e3181fc9178.

Blood Volume Heterogeneity in Syncope:

Blood volume measurement as a tool in diagnosing syncope.

Fouad-Tarazi F1, Calcatti J, Christian R, Armstrong R, Depaul M.
Am J Med Sci. 2007 Jul;334(1):53-6.

Quantifying Surgical Blood Loss:

Measurement of Blood Loss in Cardiac Surgery: Still Too Much.

Nelson M, Green J, Spiess B, Kasirajan V, Nicolato P, Liu H, Meshkin RS
Ann Thorac Surg. 2018 Apr;105(4):1176-1181. doi: 10.1016/j.athoracsur.2017.11.023. Epub 2018 Mar 3

Understanding the Heterogeneity in Volume Overload

Understanding the Heterogeneity in Volume Overload and Fluid Distribution in Decompensated Heart Failure Is Key to Optimal Volume Management

Wayne L. Miller and Brian P. Mullen
Journal of the American College of Cardiology
Vol. 2, No.3, June 2014


Clinical Evidence Nuclear Medicine

Clinical Evidence Hypertension and Syncope

Clinical Evidence Intensive and Critical Care Medicine

Clinical Evidence Surgery and Anesthesiology

Chronic Fatigue Syndrome


Additional References