BVA Product Literature

Highlights of the BVA-100

  • The BVA-100 calculates true normal blood volume for a specific individual.
  • The BVA-100 directly measures circulating blood volume in 60 minutes or less.
  • Individuals of different body sizes may have identical hematocrits but vastly different blood volumes.
  • Accurate knowledge of blood volume can prevent serious complications from undertransfusion caused by unrecognized severe hypovolemia.
  • The BVA-100 is the first instrument for the measurement of human blood volume to receive patents in the U.S., European Common Market, and Japan.
  • The BVA-100 helps differentiate the post-surgical normovolemic anemic patient from the anemic hypovolemic patient.
  • The BVA-100 can accurately ascertain individual patient’s presurgical blood volume status to enable more precise fluid replacement during and after surgery.
  • The BVA-100 provides objective data upon which physicians can base decisions to transfuse, reducing unnecessary use of blood products and physician liability.
  • The BVA-100 reduces morbidity from potentially contaminated blood by avoiding unnecessary transfusions.
  • The BVA-100 is useful in measuring blood volume in conditions complicated by fluid retention such as hepatic and renal disease.

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Product Specifications


The BVA-100 ensures accuracy in three ways:

  1. The MAX-100 syringe is engineered to deliver a 99.5% accurate dose of tracer solution.
  2. The BVA-100 provides advanced statistical analysis of data obtained during testing.

Automatic multi-point calculation with error-checking and true zero-time blood volume using real-time regression analysis ensures accuracy and the elimination of error.

  1. The BVA-100 automatically provides normal (expected) blood volumes based on deviation from ideal weight. This is easily accomplished by entering height and weight into the computer program.

Patient Safety and Comfort

  • The BVA-100 eliminates the need for potentially harmful retransfusion of labeled blood.
  • Patient test time ranges from only 30 to 45 minutes.

Ease of Use

  • Time-consuming steps of blood labeling and preparation of exactly matched standards are eliminated.
  • Calculations are automatically provided.
  • Estimated test time ranges from 60 to 90 minutes Other less sophisticated methods can take 4 to 5 hours to complete.
  • Infusion and the acquisition of multiple samples can be performed with a single venipuncture.


  • Sample changer (including shielding): 180 lb (81.65 kg)
  • Computer: 35 lb (15.88 kg)
  • Printer: 10 lb (4.54 kg)


  • All units are bench-top mounted
  • Sample changer (width, depth, height): 21 in. (53.34 cm), 26 in. (66.04 cm), 24 in. (60.96 cm)
  • Computer with keyboard and monitor (width, depth, height): 13 in. (33.02 cm), 21 in. (53.34), 16 in. (40.64 cm)
  • Printer (width, depth, height): 16 in. (40.64 cm), 14 in. (35.56 cm), 6 1/2 in. (16.51 cm)

Sample Changer

  • Sample handling: 25-sample rotary changer; change time is ten seconds per sample
  • Detector and shield: 2 in. x 2 in. (5.08 cm x 5.08 cm) sodium iodide [NaI(Tl)] with 0.8 in. x 1.4 in. (2.03 cm x 3.56 cm) deep well; shielded 4-pi by ~2 in. (5.08 cm) low-background lead; energy range: 20 to ~2000 keV.
  • Maximum background (laboratory): < 100 cpm



  • Sample changer: 3 in. (7.62 cm) at sides, 5 in. (12.7 cm) at rear, 3 in. (7.62 cm) above; there must be no obstruction underneath
  • Computer: 5 in. (12.7 cm) at sides, 4 in. (10.16 cm) at rear, 5 in. (12.7 cm) above, 6 in. (15.24 cm) at front (in addition to keyboard); there must be no obstruction of airflow at the rear
  • Printer: 4 in. (10.16 cm) at sides, 4 in. (10.16 cm) at rear, 12 in. (30.48 cm) above for paper access; there must be free air flow at sides and rear and free paper flow from below or rear


  • The sample changer requires a sturdy, laboratory-type bench capable of supporting 180 pounds (81.65 kg) on a four-point mounting; it must be level. The computer and printer require only office-type mounting facilities.


  • Observe normal laboratory conditions.


  • All units require 115 V ± 10%, 60 Hz, single phase
  • Sample changer: 40 W
  • Computer: 300 W
  • Printer: 15 W

Electromagnetic Interference (EMI)

  • All units are well-shielded against emission of EMI.

Heat Load

  • Less than 300 W are contributed to the atmosphere
  • Laboratory Environment for Gamma Counting
  • Background Radiation Limit
  • External sources of radiation can significantly affect the proper operation of the instrument and the test results. Such sources should be minimized to the greatest possible extent.

Temperature Limits

  • The BVA-100 is a precise laboratory device; it is temperature sensitive. Temperatures must be maintained within ± 5 °F (2.78 °C) of normal; the rate of change must be < 1 °F (0.56 °C) per hour
  • Operating temperature range: 65-85 °F (18-30 °C)
  • Storage temperature range: 45-100 °F (8-38 °C); rapid temperature changes must be avoided
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